Druks grew up in Tel Aviv where he studied at the Art Academy and became involved in avant-garde art and theatre circles. By the late 1960s, Druks was established as a leading young Israeli artist and decided to travel abroad. He arrived in Europe around 1970, and after a period in Holland, settled in England where he became known for his conceptual work, with solo exhibitions in the 1970s at the Museum of Modern Art, Oxford; The Whitechapel Gallery, London; De Appel, Amsterdam; and the ICA, London.